West Nile virus (WNV) mainly infects birds, but is known to infect humans, horses, dogs and other domestic animals. The main route of human infection is through the bite of an infected mosquito. Approximately 90% of West Nile virus infections in humans are without any symptoms. WNV produces three different outcomes in humans. The first is an asymptomatic infection; the second is a mild febrile syndrome termed West Nile Fever; the third is a neuroinvasive disease termed West Nile meningitis or encephalitis. The population proportion of these three states is roughly 110:30:1.
AmpliSens® WNV-FRT PCR kit is One-Step RT-PCR test for the qualitative detection of West Nile virus RNA in the clinical material (blood plasma, serum; white blood cells; cerebrospinal fluid), autopsy material of human and animals (brain tissue) and biological material (mosquitoes and ticks). Kit contains Internal Control to check RNA extraction and reverse transcription processes of each sample and to identify possible cDNA amplification reaction inhibition.