Infection by T. pallidum has diverse clinical manifestations - initial genital tract lesion followed by disseminated lesions and cardiovascular and neurologic problems and CNS disease manifested as acute syphilitic meningitis. Infection during pregnancy results in numerous birth defects or fetal death. Infections in adults are usually chronic, death or serious disability is rare.
AmpliSens® Treponema pallidum-FRT PCR kits are amplification tests for qualitative detection of T. pallidum DNA in the clinical materials (scrapes/swabs of urogenital tract mucous membranes; serous exudate of vesicles, ulcers or erosions). Kit contains Internal Control that allows detection of DNA extraction efficiency, as well as amplification process.