Parvovirus B19 is a member of the family Parvoviridae. It is classified into three genotypes: genotype 1 (classical B19 strains), genotype 2 (prototype K71- and A6-like strains) and genotype 3 (prototype V9 virus). The clinical conditions associated with the infection include erythema infectiosum (Fifth Disease), arthropathy, transient aplastic crisis, chronic red cell aplasia, hydrops foetalis and papular, purpuric eruptions on the hands and feet („gloves and socks“ syndrome). Complications thought to be associated with Parvovirus B19 infection include encephalopathy, epilepsy, meningitis, myocarditis, dilated cardiomyopathy and autoimmune hepatitis.
AmpliSens® Parvovirus B19-FRT Real-Time PCR kit is a quantitative kit based on DNA extraction from the plasma of peripheral or umbilical blood, amniotic fluid, throat washes and swabs, saliva along with Internal Control.