Most EBV infections are acquired during childhood and are asymptomatic. Symptoms, when produced, are undistinguishable from other acute viral syndromes. Many benign and malignant diseases, however, have been associated with EBV in immunocompromised patients. EBV causes Infectious mononucleosis - an acute, self limiting febrile illness in young adults, characterized by fever, sore throat, abdominal discomfort, pharyngitis, tonsillitis, tender generalized lymphadenopathy, palatal petechaie and periorbital edema, as well as with Burkitt's lymphoma. In transplant patients, early and late onset lymphoproliferative diseases are often caused by EBV.
AmpliSens® EBV-screen/monitor-FRT kit can determine quantity of EBV in 1 ml of the liquid sample or EBV DNA concentration in copies per the human cell quantity. The linear range of AmpliSens® EBV-screen/monitor-FRT PCR kit is 500– 10,000,000 copies/ml, analytical sensitivity is 400 copies/ml or 5 EBV DNA copies per 10 cells.